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Open access Sep 2026

Assessing the impact of earlier initiation of biologics on clinical remission and other outcomes in a global real-life severe asthma cohort from CHRONICLE, ISAR and OPCRD.

BACKGROUND Biologics are generally reserved for severe asthma (SA) after standard treatments have failed. Their recommendation is based on randomized controlled trials, designed to assess efficacy but not the optimal timing for biologic initiation. RESEARCH QUESTION Does the timing of biologic initiation affect SA ou...

G. Canonica, G. Christoff, Ming-Ju Tsai et al. · 0 citations
Review Aug 2026

Non-Oncology Biomarkers in Precision Medicine: A Narrative Review.

This narrative review explores the evolving role of biomarkers across cardiovascular, renal, neurological, metabolic, metabolic, and respiratory diseases, focusing on their clinical and regulatory contexts of use-diagnostic, prognostic, predictive, surrogate, safety, and pharmacodynamic/response.

Achilleas Livieratos, Laura Goea, V. Das et al. · 0 citations

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