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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

M. Gandal

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2 papers indexed here

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Open access Sep 2026

Human genetic risk for major depressive disorder implicates motor cortex PVALB⁺ inhibitory neurons

Major depressive disorder (MDD) is highly polygenic, but the cellular and anatomical contexts through which inherited risk contributes to disease biology remain incompletely understood. Here we integrated large-scale MDD genome-wide association studies with an adult human brain single-cell discovery atlas and five inde...

Y. Ma, H. Han, C. Chen et al. · 0 citations
Open access Aug 2026

Morphogen-guided neocortical organoids with anteroposterior areal identity

Summary The human neocortex exhibits characteristic regional patterning (arealization) critical for higher-order cognitive function. Disrupted arealization is implicated in neurodevelopmental disorders (NDDs), but current neocortical organoid models largely fail to recapitulate this patterning, limiting mechanistic und...

Yuan-Chen Tsai, Hajime Ozaki, Axel A. Almet et al. · 1 citation

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