Author

M. García-Gutiérrez

2 papers indexed here

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Review Open access Oct 2026

Time matters: CB2 receptor, developmental stress sensitivity and affective vulnerability

Early-life experiences are among the strongest predictors of vulnerability to emotional disorders, including depression in adulthood. Despite this association, the neurodevelopmental mechanisms underlying this link remain poorly understood. In this context, the endocannabinoid system—a neuromodulatory lipid signaling s...

A. B. Torregrosa, F. Navarrete, M. García-Gutiérrez · Frontiers in Cell and Develo... · 0 citations

Open access Sep 2026

GPR55 deletion increases anxiety- and depression-like behaviors and modifies amygdalar GABAAα2 expression

Findings indicate that loss of GPR55 heightens emotional vulnerability and alters specific GABAergic markers in the AMY while preserving HPA axis-related transcriptional response to acute stress and support GPR55 as a potential target for the modulation of anxiety- and depression-related states.

M. García-Gutiérrez, Lucía Illescas, A. Gasparyan et al. · Frontiers in Pharmacology · 0 citations