BACKGROUND & AIMS
Postoperative renal failure remains a major determinant of morbidity and mortality after cardiac surgery, with limited preventive pharmacological options. Enoximone, a phosphodiesterase III inhibitor with inotropic and anti-inflammatory properties, has shown potential for organ protection during cardi...
Francesco Zito, Kacper Piasecki, Marco Coli et al.· Heart, Lung and Circulation· 0 citations
OBJECTIVES
Readmissions after coronary artery bypass grafting (CABG) are common and contribute substantially to long-term morbidity, yet extended follow-up data remain limited. Women experience higher perioperative morbidity, mortality, and short-term readmission rates than men, but long-term sex-specific patterns of r...
M. Arnreiter, Alexandra Kaider, P. Angleitner et al.· Interdisciplinary cardiovasc...· 0 citations
Collectively, these investigations demonstrate that CPB-associated factors such as non-pulsatile flow and the kinetics of CPB initiation, early hypotension, hemodilution, hypothermia, systemic inflammation, oxidative stress, and anesthetic-induced vasodilation impair endothelial-mediated vascular responsiveness.
Ignazzo Condello, M. Dell'Aquila, S. Condello et al.· The Journal of ExtraCorporea...· 0 citations
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