Author

M. Gelléri

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Open access Sep 2026

The nuclear actin cytoskeleton supports DNA double-strand break repair via VCP-mediated extraction of the KU70/80 complex from damaged chromatin

Double-strand breaks (DSBs) are critical lesions in genomic DNA, and their accurate repair is essential for maintaining genome stability. The nuclear actin cytoskeleton has been implicated in homology-directed repair (HDR) of DSBs. However, the underlying mechanism remains poorly understood. Here, we report that Myosin...

Kristine Hauschulte, Jie Shi, Ronald P. Wong et al. · bioRxiv · 0 citations

Preprint Sep 2026

Relaxing Coherence Requirements on Laser Sources for Nanoscopy through Optical Fiber Technique

High numerical-aperture (NA) focusing of cylindrical vector beams (CVBs) typically requires costly, high-quality lasers to supply a stable vector pupil field. Here, we introduce fiber-conditioned vectorial nanofocusing, in which an optical-fiber-based mode-selective coupler projects a strongly distorted beam of a diode...

Kai-Fa Xin, Meng-Die Hou, Ao Yang et al. · 0 citations