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Author

M. Ghadimi

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3 papers indexed here

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Open access Oct 2026

A clinically annotated proteomic and histological resource of 1,000 colorectal cancers

Colorectal cancer (CRC) is heterogeneous, yet current classifications capture this heterogeneity only in part. Here we present a multimodal resource of 1,000 treatment-naïve CRC cases, the largest proteomically profiled CRC cohort to date, integrating deep proteomics, targeted genomics, whole-slide histopathology and c...

A. Qoku, N. Ullrich, F. Miranda et al. · 0 citations
Preprint Sep 2026

A Multimodal Dataset for Survival Prediction in Resected Pancreatic Ductal Adenocarcinoma

Survival research in pancreatic ductal adenocarcinoma (PDAC) is limited by the scarcity of datasets linking whole-slide histology with clinical, molecular, and long-term outcome data. We present a retrospective single-centre cohort of 302 patients who underwent PDAC resection at University Medical Center Gottingen. The...

Anh-Tien Nguyen, Mawuko Tettey, J. M. Metsch et al. · 0 citations
Open access Aug 2026

Targeting PRMT5 Inhibitor–Induced Adaptation in Pancreatic Cancer with the RBM39 Degrader Indisulam

Abstract Pancreatic ductal adenocarcinoma (PDAC) remains a formidable clinical challenge. Next-generation protein arginine methyltransferase 5 (PRMT5) inhibitors show promising clinical results in a subset of PDACs with codeletion of the tumor-suppressor CDKN2A and the methylthioadenosine phosphorylase (MTAP) gene, but...

Valentina Spielmann, Jonas Buchloh, Selen Selcen et al. · 0 citations

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