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Author

M. Gilljam

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Open access Oct 2026

T-BET promotes inflammatory specialization without driving terminal maturation of iPSC-derived NK cells

Induced pluripotent stem cells (iPSCs) provide a scalable platform for off-the-shelf immune cell therapies; however, the mechanisms controlling maturation and functional specialization of iPSC-derived natural killer (iNK) cells are not fully understood. In this study, we combined single-cell transcriptomics, phenotyp...

C. Marsal, Muhammad Kashif, Sophia Borate et al. · 0 citations
Open access Aug 2026

Oncolytic HSV1716 attenuates tumor-killing activity of infected primary NK cells

It is demonstrated that primary human NK cells are infected by HSV1716 and undergo functional and phenotypic changes, leading to a diminished cytotoxic capacity.

K. Susek, D. Holla, C. Marsal et al. · 0 citations

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