Open access
Aug 2026
Pharmacological mTOR pathway activation does not enhance trophectoderm differentiation in bovine embryos.
In conclusion, pharmacological activation of the mTOR pathway did not positively influence TE differentiation in bovine embryos; however, it effectively rescued the unexpected negative effects induced by the vehicle on TE cell number and YAP1 signaling.
M. Vilioti, Beatriz Cartaxo Ragnelli, F. Berling et al.
· Reproductive Biology · 0 citations