Bicaudal C Homolog 1 (BICC1) is a conserved RNA‐binding protein that, in mammals, has been primarily associated with polycystic kidney disease and renal organogenesis. However, its role in other disease contexts, including cancer, remains poorly understood. In this study, we characterized the BICC1 interactome, with em...
Heloísa Monteiro Do Amaral-Prado, G. A. Moreira, C. Santos et al.· FASEB bioAdvances· 0 citations
Translational control is redefined as a central checkpoint in macrophage activation, revealing how GCN2 mitigates ribosomal stress to prevent inflammatory hyperactivation, with potential therapeutic implications for TNFα-driven inflammatory diseases.
R. D. Requião, L. F. Lima-Silva, P. Estevão et al.· Journal of Biological Chemis...· 0 citations
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