Author

M. Hansen

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Open access Aug 2026

Genetic architecture of cytokine autoantibodies and associated risk of common diseases

Anti-cytokine autoantibodies are increasingly recognized as modulators of immune function and determinants of disease risk, yet their genetic basis and population-level impact remain unclear. Here we perform genome-wide association studies of autoantibodies against IL-1α, IL-6, IL-10, IFN-α, IFN-β, IFN-γ and GM-CSF in...

J. V. von Stemann, Joseph Dowsett, R. Teglgaard et al. · Nature Communications · 0 citations

Open access Sep 2026

The clinical benefit of prostacyclin treatment in mechanically ventilated patients with SARS-CoV-2 infection is not attributed to anti-inflammatory effects.

BACKGROUND Treatment with the synthetic prostacyclin analog iloprost has been shown to attenuate endothelial glycocalyx shedding and organ failure in patients with critical Covid-19. The treatment is currently being investigated in a broader setting of patients with acute respiratory failure. We here investigated the e...

Martin Vigstedt, S. McGarrity, P. Søe-jensen et al. · Cytokine · 0 citations