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Author

M. Heinig

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Open access Aug 2026

Immunological risk identified by single-cell multi-omics and cardiovascular outcomes.

BACKGROUND AND AIMS While inflammation and (auto-)immunity are modifiers of atherosclerosis, immunological determinants of cardiovascular risk beyond the established inflammatory markers, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6) remain incompletely defined in humans. This exploratory proof-o...

H. Horstmann, Nathaly Anto Michel, C. Losert et al. · 0 citations
Sep 2026

The molecular landscape of hypertrophic cardiomyopathy across disease stages and genotypes.

Unsupervised and supervised machine learning approaches distinguished HCM from dilated cardiomyopathy and accurately predicted genotype status in early-stage HCM from cell type-resolved transcriptional profiles, revealing widespread genotype-driven remodeling.

E. Adami, Yuri Kim, Sean L. Zheng et al. · 1 citation

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