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Author

M. Hijikata

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Open access Oct 2026

Deletion of ppe27 in Mycobacterium bovis BCG augments macrophage immune responses during infection

ABSTRACT Mycobacterial infection induces dynamic transcriptional changes in both the host and pathogen. In slow-growing mycobacteria, the ESX-5 secretion system plays a crucial role in virulence by exporting Pro–Glu (PE) and Pro–Pro–Glu (PPE) proteins, which modulate host immune responses and contribute to pathogenesis...

Tz-Chun Guo, Shintaro Seto, M. Hijikata et al. · 0 citations

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