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M. Hitz

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Open access Aug 2026

Brugada Syndrome in the Pediatric Population: Diagnostic Challenges and Clinical Outcome-Results of the German Multicenter Study COGIA.

INTRODUCTION Diagnosis and treatment of children and adolescents with suspected Brugada syndrome (BrS) is challenging. Aim of the study was to evaluate the applicability of current diagnostic criteria for pediatric patients with suspected BrS in the German multicenter study COGIA and to assess clinical outcome. METHO...

Lea Lippert, T. Burkard, F. Markel et al. · 0 citations
Open access Sep 2026

Transcriptional dynamics of the murine heart during perinatal development at single-cell resolution

ABSTRACT Heart maturation and remodelling during the foetal and early postnatal period are critical for the proper survival and growth of the foetus, yet our knowledge of the molecular processes involved is lacking for many cardiac cell types. To gain a deeper understanding of the transcriptional dynamics of the heart...

Lara Feulner, F. Wünnemann, Naimeh Rafatian et al. · 0 citations
Review Open access Aug 2026

Molecular characterization of FAM222B as a novel disease gene for dominant cardiovascular laterality defects

This work proposes FAM222B as a novel candidate gene for cardiovascular laterality defects, described as a substrate of Nemo-like kinase (NLK), associated with left–right body axis determination in zebrafish homologues, fam222ba/bb, and fam222aa.

Nina Reitz, J. Lambertz, Öznur Yılmaz et al. · 0 citations

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