Author

M. Hornef

2 papers indexed here

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Open access Sep 2026

mTORC1-TFEB/TFE3 signaling is associated with bile acid diversification during hepatic metabolic adaptation

The mechanistic target of rapamycin complex 1 (mTORC1) integrates nutrient and hormonal cues to regulate hepatic lipid metabolism with major implications for metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we show that altered hepatic mTORC1–TFEB/TFE3 signaling is associated with coordinated rem...

A. Zaufel, Wenfei Sun, N. Pastore et al. · Science Advances · 0 citations

Open access Aug 2026

Developmental factors drive the compartmentalized and discontinuous maturation of the small intestinal epithelium during the early postnatal period

The temporal, spatial, and cellular diversity of the small intestinal epithelium during the postnatal period, a critical time window that accompanies the transition from placental energy supply to enteral feeding, and the establishment of the enteric microbiota and postnatal immune maturation, has not been systematical...

Johannes Schöneich, Aline Dupont, Stefan Schlößer et al. · PLoS Biology · 0 citations