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Author

M. J. Dalby

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Open access Aug 2026

Remodeling of lipid metabolism orchestrates human adipose-derived mesenchymal stem cells osteodifferentiation.

Mesenchymal stem cell (MSC) osteodifferentiation involves adaptations of lipid metabolism but the specific regulatory roles of lipid species remain underexplored. We use a global metabolomics approach, comprising LC-MS lipidomics and NMR metabotolomics, to identify mechanistic features of human adipose-derived MSC (hAM...

Daniela S C Bispo, Jennifer H. Haggarty, Inês C. R. Graça et al. · 0 citations
Open access Sep 2026

iPSC-Derived Chondroprogenitors as a Promising Cell Source for Cartilage Engineering: A Comparison with MSCs in Unmodified and Peptide-Functionalized Alginate Hydrogels

Articular cartilage degeneration is a hallmark of degenerative joint diseases, yet its limited regenerative capacity poses significant challenges for tissue engineering. While mesenchymal stem cells (MSCs) are the most commonly employed cell type in cartilage tissue engineering, they exhibit donor variability, restrict...

M. L. Vieri, Andrew R. Thomson, M. J. Dalby et al. · 0 citations

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