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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

M. Juan

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2 papers indexed here

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Sep 2026

Chimeric HLA Antibody Receptor (CHAR) T Cells to Specifically Eliminate HLA-DQ-Specific B Cells.

BACKGROUND CAR T cell therapy has revolutionized the treatment of hematological malignancies by effectively eliminating tumor cells. In the field of kidney transplantation, comparable cellular therapies are being explored to facilitate transplantation and prevent graft rejection. Chimeric HLA antibody receptor (CHAR) T...

Carolt Arana, I. Gille, R. Hagedoorn et al. · 0 citations
Open access Aug 2026

Impact of IL-21 on CAR T-cell manufacturing: phenotypic, metabolic, and functional outcomes

Introduction Cytokines used during chimeric antigen receptor (CAR) T-cell manufacturing can influence product differentiation and functional fitness. Methods We investigated whether adding IL-21 to an IL-7 + IL-15 expansion regimen modulates CD84-directed CAR T cells (CART84) targeting CD84+ acute myeloid leukemia (AML...

Maria Val-Casals, Ane Altuna, L. Pérez-Amill et al. · 0 citations

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