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M. Kähönen

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Open access Aug 2026

Intergenerational and life-course links between a cardiovascular health-related methylation score and early vascular changes

An LE8-derived DNAm score was associated with lower cIMT across the life course and, to a lesser extent, across generations, suggesting that blood DNAm reflects cumulative cardiovascular health and vascular burden and may complement conventional cardiovascular risk assessment.

B. Mishra, E. Raitoharju, L.-P. Lyytikäinen et al. · 0 citations