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Open access Sep 2026

Enhanced 3D Osteogenic Differentiation of Encapsulated Human MSCs in Hyaluronic Acid Core Alginate Shell Capsules under Dynamic Culture Conditions

The growing demand for three-dimensional (3D) in vitro models that accurately replicate human tissue to investigate disease mechanisms, enable tissue replacement, and support drug testing is driving the need for more advanced manufacturing platforms. Mesenchymal stem/stromal cells (MSCs) are promising candidates for ti...

Julia Dreger, Daniela Andrea Contreras-Pérez, M. Keck et al. · 0 citations
Aug 2026

Determinants and clinical impact of ischemia time in microsurgical breast reconstruction: A multicenter registry analysis of 4209 flaps.

BACKGROUND Ischemia time is a key determinant of microsurgical free-flap survival and potentially modifiable risk factor in autologous breast reconstruction. However, factors influencing ischemia time within complex workflows are insufficiently understood. Existing evidence is largely limited to single-center, retrospe...

U. von Fritschen, M. Keck, S. Fertsch et al. · 0 citations

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