Review
Open access
Aug 2026
Routes to colorectal cancer in Lynch syndrome: a decade of molecular and clinical insights converging on Schrödinger’s cat
Colorectal cancer (CRC) development in Lynch syndrome (LS) has long been regarded to follow an adenoma-carcinoma sequence accelerated in comparison to microsatellite-stable (MSS) CRC development. Yet, several clinical observations challenged this hypothesis, most notably the persistently high CRC incidence under colono...
A. Ahadova, Fatima Fayyaz, Leon Marin Grez et al.
· Familial Cancer · 0 citations