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M. Komelkova

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Review Open access Jul 2026

Anti-Inflammatory and Antioxidant Strategies in Epilepsy: From Molecular Mechanisms to Threshold Management

This work proposes a threshold management framework for DRE, built on a revised reservoir model, and translates it into three structural priorities: mechanistic phenotyping to stratify patients by pathophysiological domain, dual-mechanism drug development, and trial designs suited to multicomponent, context-dependent interventions.

Alexander Trofimov, Ksenia Shcherbakova, Alexander Schwarz et al. · 0 citations