Author

M. Kudryashev

2 papers indexed here

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Open access Sep 2026

Ligand-induced activation of RyR1 in native membranes

Synchronized calcium release through arrays of the ryanodine receptor RyR1, fundamental to skeletal muscle excitation-contraction coupling, is achieved through the mechanical interaction of RyR1s and voltage-sensing receptors DHPR that activate RyR1s in response to action potentials. The calcium release is enhanced thr...

Vasilii Mikirtumov, Sabrina Golusik, Rui-Feng Huo et al. · Nature Communications · 0 citations

Open access 2026

Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.

Transmembrane signalling by membrane proteins is essential for physiological processes and disease states, making these proteins key targets for drug development. Structural biology provides unique insights into the mechanisms of membrane protein function and dysfunction caused by mutations. Most high-resolution membra...

I. M. Souza-Silva, Uljana Kravčenko, Xiaofeng Chu et al. · Methods in molecular biology · 0 citations