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M. L. Wise

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Review Open access Sep 2026

Dapagliflozin Beyond Glucose Lowering: Mechanisms of Renal and Systemic Protection

Sodium glucose cotransporter-2 inhibitors (SGLT2is) have rapidly evolved from glucose-lowering agents to multifaceted therapies with significant renoprotective and cardioprotective potential. Although originally developed to inhibit glucose reabsorption within the renal proximal tubule for the treatment of Type 2 diabe...

M. L. Wise, A. Alli · 0 citations

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