Jul 2026
Efficient CRISPR/Cas9-mediated homology independent sequence replacement in vivo and non-dividing primary cells
REPLACE is established as a versatile platform for homology-independent sequence replacement and as a complementary approach for genetic correction in settings where homology-directed repair (HDR), base editing (BE) or prime editing (PE) are inefficient or not applicable.
Tu Dang, Alexandra Roman, Anja Zimmer et al.
· bioRxiv · 0 citations