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M. Liedtke

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Review Open access Jul 2026

Exercise-induced BDNF signaling mediates neuroplasticity in depression

Background.Major depressive disorder (MDD) is increasingly recognized as a disorder of impaired neuroplasticity. Brain-derived neurotrophic factor (BDNF) plays a central role in neuronal survival, synaptic plasticity, and antidepressant mechanisms [1–4]. Physical exercise has emerged as an effective non-pharmacological...

P. Turzyńska, M. Liedtke, Alicja Biskup et al. · 0 citations

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