Genetic associations with EEG signatures in mild cognitive impairment: insights into Alzheimer's disease pathophysiology
The convergence of candidate genes on synaptic, neurodevelopmental and neuroinflammatory pathways, and genetically informed clustering linked to plasma p-tau217 and delayed verbal recall, supports the use of EEG-derived endophenotypes for dissecting heterogeneity in early cognitive decline and AD-related pathology.