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Open access Sep 2026

Towards reconstruction of the human interactome from positive and negative experimental evidence

Protein-protein interactions (PPIs) have been detected and reported in the millions, but while they are used in many different contexts for better understanding cellular processes in health and disease, the knowledge of the human PPI network is far from complete, containing many false positive measurements and being hi...

Joel Ås, K. Pelz, J. Bernett et al. · 1 citation
Open access Sep 2026

Comprehensive and bias-aware analysis of small RNA NGS data for biomarker detection with caRNAge

Aim: Small RNA sequencing (small RNA-Seq) is a widely used and important method for biomarker discovery in extracellular vesicles (EVs), which carry small RNAs among their cargo and protect them from degradation in liquid biopsies. However, existing computational tools for small RNA-Seq data are not tailored to EV-RNA....

B. Kirchner, C. Grätz, Johannes Kersting et al. · 0 citations

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