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M. Lohde

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Open access Sep 2026

Large-scale benchmarking of prokaryotic annotation tools across thousands of species

This study presents the first large-scale investigation of four prominent open-source annotation tools (Prokka, Bakta, EggNOG-mapper, and PGAP) across 156,033 diverse genomes, highlighting tool-specific strengths crucial for selecting optimal solutions based on genome quality, taxonomy, and origin.

Mateusz Jundzill, Martin Hölzer, S. Mangul et al. · 0 citations
Open access Aug 2026

Experimental evolution of phage K enhances antibacterial activity against USA300 MRSA in lung infection models

Findings highlight the value of experimental evolution for tailoring therapeutic phages and support phage adaptation as a promising strategy for developing interventions against multidrug-resistant S. aureus.

Swanti Schapp, P. Seibold, Yasmina Reisser et al. · 0 citations

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