Author

M. Lutolf

2 papers indexed here

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Open access Sep 2026

Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids

ABSTRACT Cell state, growth, and mechanics are tightly connected properties underpinned by fundamental biological processes. Yet methods to quantify them simultaneously under physiologically relevant conditions, at resolutions sufficient to follow (sub)cellular processes, are still lacking. In particular, the correlati...

Ilaria Incaviglia, Giulia E. M. Ammirati, S. Herzog et al. · Advancement of science · 0 citations

Open access Aug 2026

Early functional reactivity to a CEACAM5 x CD3 T cell bispecific antibody in solid tumors associates with baseline immune contexture rather than target antigen density alone

Clinical translation of T cell bispecific (TCB) therapies in solid tumors is hindered by the immunosuppressive tumor microenvironment and intratumoral heterogeneity, features poorly captured by standard preclinical models. We applied an integrated translational framework, combining humanized mouse models, a patient-d...

Sabine Wilson, Abraham Silva, M. Serrano-Serrano et al. · npj Precision Oncology · 0 citations