Synthesis and Characterization of Substituted Isoxazolidines through 1,3-Dipolar Cycloaddition and Evaluation of their Antibacterial, Antioxidant and Molecular Docking Studies
A series of substituted isoxazolidine derivatives (3a-g) was synthesized through a 1,3-dipolar [3+2] cycloaddition of a glutaraldehyde-derived nitrone with substituted cinnamaldehyde-derived chalcones. The synthesized derivatives were evaluated for their in vitro antibacterial activity against selected Gram-positive an...