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M. Mapstone

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Open access Sep 2026

Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in a multiethnic US population

Neuroinflammation is associated with depression and anxiety risk, both of which demonstrate a bilateral relationship with cardiometabolic disorders. Systemic inflammation was also commonly described in patients with cardiometabolic disorders. It is, thus, unclear whether pro-inflammatory cytokines might statistically m...

Asma Hallab, S. O'Bryant, Kristine Yaffe et al. · 0 citations
Open access Aug 2026

Multi-dimensional attention framework for personalised Alzheimer's disease progression prediction across sporadic and genetic risk cohorts

A multi-dimensional attention framework that simultaneously captures both temporal dynamics and biomarker importance to predict disease progression across three fundamentally different populations could enable precision medicine approaches for data-limited cohorts across the Alzheimer's disease spectrum.

Zhi-Yuan Song, Si-Yang Song, Isabel C. H. Clare et al. · 0 citations
Open access Jul 2026

Parallel neuroinflammatory pathways to cerebrovascular burden and amyloid beta in Alzheimer's disease

Higher plasma YKL‐40 was associated with greater white matter hyperintensity (WMH), whereas higher plasma GFAP was related to increased 18F‐florbetapir (FBP) standardized uptake value ratio (SUVR) and higher plasma p‐tau217 was associated with reduced MTL cortical thickness and hippocampal volume.

Batool Rizvi, Jenna N. Adams, Alison R. Bamford et al. · 1 citation

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