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M. Mesulam

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Open access Sep 2026

Unraveling changes in mitochondrial processes influenced by ancestry in APOEε4 carriers with Alzheimer disease

The APOEε4 allele is the strongest known genetic risk factor for late-onset Alzheimer disease (AD). However, the risk effect of APOEε4 varies substantially by ancestry, with individuals of African ancestry (AF) demonstrating markedly lower risk compared to those of European ancestry (EU). This difference in r...

M. D. M. Muniz Moreno, K. Celis, F. Rajabli et al. · 0 citations

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