Author

M. Middeldorp

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Open access Sep 2026

Leadless Pacemaker, Right Ventricular Pacing Burden, and Heart Failure.

BACKGROUND The optimal right ventricular pacing burden (%RVP) threshold associated with heart failure (HF) in patients with leadless pacemakers (LPs) remains unclear, whereas thresholds of 20% and 40% have been commonly used in studies of transvenous pacemakers. OBJECTIVE To assess the current %RVP cutoffs and explor...

H. Iwakawa, M. Middeldorp, S. Kakarla et al. · Heart Rhythm · 0 citations

Review Open access Aug 2026

Non-linear associations between blood pressure and clinical outcomes in atrial fibrillation: A systematic review and dose-response meta-analysis.

Systolic blood pressure exhibits a U-shaped relationship with all-cause mortality in patients with AF, balancing against a monotonic increase in ischemic stroke and intracranial haemorrhage at higher pressures, appears to optimize the balance between stroke prevention, bleeding risk, and survival.

E. Shahmohamadi, Alessandra Pina, Adrian D. Elliott et al. · Europace · 0 citations