Author

M. Molina-Vila

2 papers indexed here

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Review Open access Aug 2026

Tumor microenvironment and signaling pathways in melanoma brain metastasis

Melanoma has one of the highest propensities to metastasize to the brain, and despite major advances with immune checkpoint inhibitors, brain metastases remain a leading cause of morbidity and mortality. The biological mechanisms governing brain colonization, immune evasion, and resistance to therapy are incompletely u...

R. Rosell, M. González-Cao, D. Olmo-Gónzalez et al. · Annals of Translational Medi... · 0 citations

Open access Aug 2026

Anticancer effects of an XPO1 inhibitor (selinexor) with sotorasib following omeprazole preconditioning in KRAS G12C-mutant non-small cell lung cancer cells in vitro and in a mouse tumor xenograft

Background KRAS G12C-mutant advanced non-small cell lung cancer (NSCLC) is currently treated with KRAS G12C covalent inhibitors, such as sotorasib, or RAS (ON) G12-selective inhibitors; however, response rates and progression-free survival remain limited, with recurrence occurring in most patients. Although mechanisms...

Jessica González, Xue-Ting Cai, Wenjing Diao et al. · Neoplasia · 0 citations