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Review Open access Aug 2026

Reframing sarcopenia as a disease of the ageing motor system.

Sarcopenia is a major driver of disability, frailty, and loss of independence in ageing populations. Current consensus definitions have shifted from low muscle mass to low muscle strength and impaired physical performance as the defining clinical features. The underlying disease model, however, has remained predominant...

L. B. R. Orssatto, W. D. Arnold, L. Ferrucci et al. · 1 citation

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