Author

M. Parsek

2 papers indexed here

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Open access Aug 2026

Mucin promotes Psl production and surface exploration in Pseudomonas aeruginosa

ABSTRACT In chronic, recalcitrant infections, Pseudomonas aeruginosa forms biofilm aggregates that are encapsulated in a protective extracellular matrix made of exopolysaccharides, extracellular DNA, and matrix proteins. Biofilm formation is a major cause of antibiotic clearance failure in P. aeruginosa, and there is g...

S. Lamont, Matthew J Pestrak, M. Parsek et al. · mBio · 0 citations

Open access Aug 2026

Analysis of the DNA-binding domain of the Pseudomonas aeruginosa quorum sensing transcription factor LasR

It is discovered that some DNA-binding mutations can expand the range of LasR-regulated genes, which provides insight into understanding what promoters LuxR homologs bind to and, more generally, how these proteins might evolve over time to change the group of genes that they regulate.

Zichu Yang, Anvita Billa, Aditya S. Desai et al. · bioRxiv · 0 citations