Author

M. Pogorelyy

2 papers indexed here

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Open access Oct 2026

Multidimensional molecular profiling reveals decidual and circulating NK cell dynamics in early and late pregnancy.

BACKGROUND Human pregnancy presents a unique physiological state that allows for growth of an antigenically dissimilar foetus. The immune system plays a key role in establishing and maintaining successful pregnancy, yet detailed understanding of immunological responses in pregnancy is lacking. METHODS We defined the...

Jennifer R. Habel, Thi H. O. Nguyen, L. Allen et al. · EBioMedicine · 0 citations

Open access Sep 2026

Uneven TCR chain pairing constraints govern epitope recognition.

Combinatorial pairing of independently recombined T cell receptor (TCR) α- and β-chains is central to diversifying the TCR repertoire. Although sequence motifs in one chain correlate with epitope recognition, the extent to which a single chain dictates specificity remains unclear. Here, we systematically tested TCR cha...

Anastasia A. Minervina, M. Pogorelyy, K. Mayer-Blackwell et al. · Science · 0 citations