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M. Ponnusamy

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Aug 2026

Abexinostat attenuates temozolomide-resistant glioma stem cells.

BACKGROUND Glioblastoma (GBM) is the most common adult primary brain malignancy. Recent studies demonstrate that temozolomide (TMZ) facilitates the persistence of quiescent glioma stem cells (GSCs), which are responsible for GBM recurrence. An ideal therapy should eradicate both proliferating cells and GSCs. Abexinosta...

Balaji Perumalsamy, Raghupathy Vengoji, Anand Thiraviyam et al. · 0 citations
Open access Aug 2026

Malignant epithelial diversification and inflammatory neutrophil remodeling define a transitional stage between tumor cell dissemination and overt metastatic outgrowth in breast cancer

A transitional stage between tumor cell dissemination and overt metastatic outgrowth characterized by malignant epithelial diversification and inflammatory neutrophil remodeling is defined, providing a framework for investigating biomarkers and therapeutic vulnerabilities during this poorly accessible phase of metastat...

R. Pathania, Brian N. Papas, J. Kosak et al. · 0 citations

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