Dihydropyrimidinones as Potential Direct Renin Inhibitors: In Silico Molecular Docking and Molecular Dynamics Approach
This study contributes to ongoing efforts to address the global health challenge of hypertension by in silico exploring new inhibitors of the renin-angiotensin-aldosterone system (RAAS). Renin, a key enzyme regulator in this pathway, was selected as the molecular target for treatment intervention. Specifically, the pot...