Open access
Oct 2026
Integrated clinical and polygenic coronary artery disease risk score predicts 10-year progression of coronary artery plaque
Coronary artery disease (CAD) is highly heritable and clinical risk scores may insufficiently capture the full spectrum of individual risk. We investigated whether integrated polygenic risk score (iPRS) derived from a combination of genetic and clinical risk factors is associated with coronary plaque phenotypes a...
B. Weijs, N. Nurmohamed, D. Ratman et al.
· European Heart Journal · 0 citations