Author

M. Radanova

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Review Open access Oct 2026

Complement in HER2-Positive Breast Cancer: A Conditionally Protective Mechanism Under Attack

The therapeutic efficacy of anti-HER2 monoclonal antibodies in breast cancer has traditionally been attributed to direct inhibition of signaling and antibody-dependent cellular cytotoxicity (ADCC). Recent evidence, however, has established complement activation through the classical pathway as a possible adjunct mechan...

D. Petkova, Ivaila Kuleva, Zhasmina Stoyanova et al. · Antibodies · 0 citations

Open access Oct 2026

Real-World Renal Effects of Dapagliflozin in Bulgarian Patients with Chronic Kidney Disease of Predominantly Glomerular Origin: A Two-Year Comparative Cohort Study with Historical Controls

Background/Objectives: Sodium–glucose cotransporter 2 (SGLT2) inhibitors are established in the treatment of chronic kidney disease (CKD), but evidence in CKD caused by glomerular disease is limited, and patients on intensified immunosuppression have been excluded from the randomised trials. We examined the effect of d...

Veronica Aladzhova, Teodora Ilieva, Bilyana Vasileva et al. · Biomedicines · 0 citations