Effects of a selective 5-HT4 agonist and an alpha-2 adrenoceptor antagonist on etorphine-induced impairment across the oxygen cascade in immobilised sheep (Ovis aries): a randomised, prospective, and controlled trial
Etorphine profoundly impaired multiple sequential steps of the oxygen cascade in sheep, resulting in hypoxaemia, reduced DO 2 , and compensatory increases in ER, and future research is needed to develop targeted strategies that address the key mechanisms underlying the disruptions in the oxygen cascade during etorphi...