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Author

M. Ramar

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Review Sep 2026

PDK1 signaling in cancer: Current status and future perspectives.

Experimental results from breast, lung, gastric, liver, hematological, and melanoma models suggest that dysregulated PDK1 signaling can increase the output of the PI3K-AKT-mTOR pathway, invasion, metabolic adaptation, and resistance to specific hormonal, chemotherapeutic, and targeted therapies.

Darshana Ballagere Honnasiddappa, M. Ramar, Tincy Biju et al. · 0 citations
Review Jul 2026

Data Collection and Management for AI-Based Pharmaceutical Formulation Development: A Comprehensive Review.

Evidence on Real-World Data (RWD) integration with Artificial Intelligence (AI) for enhanced Adverse Drug Reaction (ADR) detection, evaluates generative AI like ChatGPT-4 and LLaMA-2 in Substance Use Disorder (SUD) scenarios, discusses current applications, and outlines future directions is synthesized.

Pritam Kayal, Priya Manna, Ramit Rahaman et al. · 0 citations

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