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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

M. Ranek

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Open access Jul 2026

Sulfotransferase signaling sustains fibroblast identity and antagonizes therapeutic cardiac reprogramming

It is shown that the sulfotransferase CHST7 stabilizes fibroblast fate via CD44/JUNB signalling, and that its inhibition enhances cardiac reprogramming and improves heart repair, and defines a sulfotransferase-dependent barrier to cell fate conversion with therapeutic implications for heart regeneration.

Michaela R. Romero, S. Murphy, Yu-Zhu Chang et al. · 0 citations
Open access Aug 2026

Domain-dependent uncoupling of the co-chaperone and E3 ubiquitin ligase CHIP underlies heterogeneity in spinocerebellar ataxia 48

Analysis of SCA48-associated variants spanning the TPR and U-box domains indicates that SCA48 results from domain-specific disruption of CHIP's dual functions, producing varying degrees of CHIP insufficiency and/or gain-of-toxic effects that together contribute to the phenotypic diversity observed across patients.

S. Altinok, E. Paulakonis, Michael F. Almeida et al. · 0 citations

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