Review
Open access
Sep 2026
Overcoming Biophysical Barriers in Melanoma Photomedicine: From Photodynamic Therapy to Smart Nanodelivery and Photoimmunotherapy
Malignant melanoma presents formidable therapeutic challenges due to optical shielding and free-radical scavenging by endogenous melanin, profound tumor microenvironment hypoxia, and aggressive metastatic dissemination, rendering conventional photodynamic therapy (PDT) clinically immature. This narrative review compreh...
F. Russano, L. Dall'Olmo, D. Brugnolo et al.
· International Journal of Mol... · 0 citations