Open access
Sep 2026
Arrest of human spermatogenesis at the pachytene stage is frequently accompanied by disruption of the piRNA pathway
The data suggest that defective piRNA processing can be linked to arrest of spermatogenesis at the pachytene stage in half of the cases and establishes the piRNA pathway as a frequent and central determinant of human spermatogenic arrest with a distinctive molecular signature of impaired germ‑cell differentiation.
G. Saritaş, S. Winge, L. Sørensen et al.
· Cell Death Discovery · 0 citations