Open access
Jul 2026
Engineering allogeneic type 1 regulatory T cells: a scalable, off-the-shelf platform for restoring immune tolerance
Phenotypic and functional analyses of TRX103 revealed the acquisition of a distinct cellular identity characterized by reduced expression of activation and immune synapse–associated molecules and minimal allogeneic stimulatory capacity, which define a distinct immunomodulatory profile for TRX103 and support its clinica...
M. Uyeda, Audrey Re, Chun-Yi Tang et al.
· Frontiers in Immunology · 0 citations