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Author

M. Rubio

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Open access Aug 2026

IL-12 restores the sequential cytotoxic capacities of anti-GD2 CAR-T and CAR-iNKT cells against glioblastoma

The mechanisms through which GBM cells evade GD2-targeted CAR-T and CAR-iNKT cells effectively target GBM but are susceptible to repeated antigen exposure, which IL-12 could counteract, and encourage further development of armored IL-12 CAR-T or CAR-iNKT cells.

Tan-Dai Tran, Cindy Lamorlette, Loris Gerard et al. · 0 citations
Open access Sep 2026

Scalable expansion of human iNKT cells: single-cell profiling and in vivo control of GvHD with preserved GvL activity

A scalable culture system to preferentially expand human CD4− iNKT cells directly from total peripheral blood mononuclear cells (PBMCs) using alpha-galactosylceramide (α-GalCer) and optimized cytokine conditions and IL-15 was the most effective cytokine.

Jordan Brouard, Cristina Caraiman, Ghislain Fievet et al. · 0 citations

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