The Expanding Landscape of Acidophilic Protein Kinases
Acidophilic kinases are serine/threonine protein kinases that preferentially phosphorylate substrates bearing negatively charged determinants near the phosphoacceptor site. These determinants may be encoded by aspartate or glutamate, or introduced by prior phosphorylation of serine, threonine, or tyrosine residues. CK2...