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Open access Jul 2026

Clonal hematopoiesis is enriched in melanoma and associated with genotype-specific differences in tumor growth and survival

Background The clinical significance of clonal hematopoiesis of indeterminate potential (CHIP) in melanoma remains incompletely defined, particularly with respect to CHIP genotype, clone size, and somatic mutations (e.g BRAF mutations). We integrated human cohort data and a syngeneic melanoma mouse model to evaluate wh...

M. Alford-Holloway, S. Reed, Y. Pershad et al. · 0 citations

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