Author

M. Schierup

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Open access Aug 2026

Intra-specific evidence to support the drift-barrier hypothesis of mutation rate evolution

The results provide support for the DBH identifying elevated mutation rates in populations subject to strong genetic drift and suggest that maternal age associates positively with µ, and shorter generation time elevates per-year mutation rates.

Chao-Wei Zhang, Hong-Bo Wang, Kerry Reid et al. · bioRxiv · 0 citations

Open access Sep 2026

Arrest of human spermatogenesis at the pachytene stage is frequently accompanied by disruption of the piRNA pathway

The data suggest that defective piRNA processing can be linked to arrest of spermatogenesis at the pachytene stage in half of the cases and establishes the piRNA pathway as a frequent and central determinant of human spermatogenic arrest with a distinctive molecular signature of impaired germ‑cell differentiation.

G. Saritaş, S. Winge, L. Sørensen et al. · Cell Death Discovery · 0 citations